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How Low Testosterone Affects Premature Ejaculation

Facts about Premature Ejaculation and treament options at National Male Medical ClinicsPremature ejaculation describes the state in which a man ejaculates earlier than he or his sexual partner desires for him to.  It is one of the biggest complaints. It can occur before penetration or right after penetration or during the beginning of intercourse.  When it occurs, both partners are usually unsatisfied with the sexual experience.  The amount of men that experience premature ejaculation is not clear but estimates (from various sources such as the National Health and Social Life Survey) range from 30 – 70% in the United States which indicates that the problem is common and likely experienced by most men at some point in life. Low T symptoms are well known as the biggest complaint that men have about their sexual performance.  People don’t usually have any particular physical signs of the problem or have any abnormal medical lab tests.  Nonetheless, premature ejaculation is a serious problem which affects the well being of millions of men. This article focuses on the causes of premature ejaculation and the role of low testosterone in the development of this condition.

Causes of Premature Ejaculation

Premature ejaculation is quite common among men.  The causes are variable and rarely physical.  The most common cause is anxiety and too much stimulation prior to sexual intercourse during the early stages of a relationship.  During the course of a relationship, guilt and other psychological factors may play a role.  In general, this problem is viewed as stemming from one’s psychological/mental state.  Usually the condition improves without treatment.  Most men use mental or physical techniques to prevent themselves from ejaculating as a result of these causes.  However, there are times when premature ejaculation is cause by factors that are not psychological.

Role of Testosterone

In some cases, testosterone plays a role in premature ejaculation.  The connection to testosterone comes from the connection to erectile dysfunction, a condition during which men are persistently unable to develop and maintain erections.  As men age, testosterone levels decline and erectile dysfunction becomes a problem.  In addition to this problem, premature ejaculation may become more common.  The connection between erectile dysfunction and premature ejaculation continues to be studied, but there appears to be an association between these two problems that impact sexual performance at various ages.  Of course, the associated will vary based on a number of other factors related to a man’s health and well being, such as his weight (measured by body mass index), cardiovascular state, and neurological state.  One recent study explores this association by suggesting that some men with premature ejaculation who have low serum levels of a hormone called prolactin also

have erectile dysfunction (low testosterone is one risk factor for this).  The importance of this connection is that the treatment of erectile dysfunction may decrease premature ejaculation.

Erectile dysfunction is better understood than premature ejaculation and has more useful treatments.  For example, drugs such as Viagra can improve erectile dysfunction and may make premature ejaculation less likely or allow men to continue performing sexually after premature ejaculation.  Also, erectile dysfunction caused by depression can be addressed by antidepressants, such as SSRIs, some which are also known to prolong erections as one of their side effects.  In addition, testosterone replacement therapy may be a useful treatment approach for men with low levels of testosterone associated with age.  Various methods of administering testosterone (such as patch, gel, or injection) make this treatment more amenable to men with busy lives or those who have preferred methods of drug administration.

Although the connection to erectile dysfunction can expand the treatment options for premature ejaculation, there is currently no drug approved by the US Food and Drug Administration specifically for premature ejaculation.  As stated, there are some studies which support the idea of using a type of drug called SSRI’s which are usually used as an antidepressant.  One side effect is a prolonged erection.  This drug can be prescribed by a physician off label.  Otherwise, the options are limited.  Thus a good assessment of a man’s testosterone level is important for making sure this is not leading to erectile dysfunction which may be impacting the problem of premature ejaculation.

National Male Medical Clinics offers superior options for

Premature Ejaculation. Anti-depressants have been commonly prescribed for PE however because of commonly experienced side-effects see your physician or National Male Medical Clinics for other available solutions.


Lue TF, Broderick GA. Evaluation and nonsurgical management of erectile dysfunction and premature ejaculation. In: Wein AJ, ed. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 22.

Shafer LC. Sexual disorders and sexual dysfunction. In: Stern TA, Rosenbaum JF, Fava M, Biederman J, Rauch SL, eds. Massachusetts General Hospital Comprehensive Clinical Psychiatry. 1st ed. Philadelphia, Pa: Mosby Elsevier; 2008:chap 36.

Corona G, Mannucci E, Jannini EA, Lotti F, Ricca V, Monami M, et al. Hypoprolactinemia: A New Clinical Syndrome in Patients with Sexual Dysfunction. J Sex Med. Feb 10 2009;[Medline]

Jannini EA, Lenzi A. Epidemiology of premature ejaculation. Curr Opin Urol. 2005 Nov;15(6):399-403.



Kilic S, Ergin, H, Baydinc YC. Venlafaxine extended release for the treatment of patients with premature ejaculation: a pilot, single-blind, placebo-controlled, fixed-dose crossover study on short-term administration of an antidepressant drug. Int J Androl. 2005;28:47. http://men.webmd.com/guide/overcoming-ejaculation-problems